Recent work on receptor molecules and cells used prototypical sweet, salty, sour, bitter, and umami stimuli. Labeled-line coding was supported, but it remains possible that the molecules and cells could respond to other tastants. Studies with other tastants are needed. The sensory message might contain two codes – one for attraction or aversion, the other, across-fiber patterning of stimulus quality.

In this interview Christine M. Korsgaard answers several questions on her particular interpretation of Kant's moral philosophy. More specifically, she dwells on the role of the noumenal/phenomenal distinction for a better understanding of Kant's idea of practical reason, as well as on the compatibility between Aristotelian and Kantian practical reason. In addition, she answers a couple of more general questions on the perspectives and challenges of contemporary ethical theory.

The purpose of this paper is twofold: firstly, to explore the emotional aspects underlying classroom conflict management, and secondly, to apply these notions to the contrasted analysis of two case studies. Our findings underscore the importance of examining teachers’ emotional regulation to better understand their performance when dealing with conflicts that affect classroom climate. In the final section, we make suggestions for introducing this perspective into initial teacher training through the use of Virtual Reality, a scenario that would allow pre-service (...) teachers to experiment, record and reflect on affective and attitudinal issues that are decisive for effective classroom conflict management. (shrink)

One cue that may facilitate children's word learning is iconicity, or the correspondence between a word's form and meaning. Some have even proposed that iconicity in the early lexicon may serve to help children learn how to learn words, supporting the acquisition of even noniconic, or arbitrary, word–referent associations. However, this proposal remains untested. Here, we investigate the iconicity of caregivers’ speech to young children during a naturalistic free‐play session with novel stimuli and ask whether the iconicity of caregivers’ speech (...) facilitates children's learning of the noniconic novel names of those stimuli. Thirty‐four 1.5‐2‐year‐olds (19 girls; half monolingual English learners and half bilingual English‐Spanish learners) participated in a naturalistic free‐play task with their caregivers followed by a test of word‐referent retention. We found that caregivers’ use of iconicity, particularly in utterances in which they named the novel stimuli, was associated with the likelihood that children learned that novel name. This result held even when controlling for other factors associated with word learning, such as the concreteness and frequency of words in caregiver speech. Together, the results demonstrate that iconicity not only can serve to help children identify the referent of novel words (as in previous research) but can also support their ability to retain even noniconic word‐referent mappings. (shrink)

In this article, we present results from a literature review of intrinsic, instrumental, and relational values of nature conducted for the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services, as part of the Methodological Assessment of the Diverse Values and Valuations of Nature. We identify the most frequently recurring meanings in the heterogeneous use of different value types and their association with worldviews and other key concepts. From frequent uses, we determine a core meaning for each value type, which is (...) sufficiently inclusive to serve as an umbrella over different understandings in the literature and specific enough to help highlight its difference from the other types of values. Finally, we discuss convergences, overlapping areas, and fuzzy boundaries between different value types to facilitate dialogue, reduce misunderstandings, and improve the methods for valuation of nature's contributions to people, including ecosystem services, to inform policy and direct future research. © 2023 The Author(s). Published by Oxford University Press on behalf of the American Institute of Biological Sciences. (shrink)

Bentley et al.--O’Brien bypass the relevance of emotions in decision-making, resulting in a possible over-simplification of behavioral types. We propose integrating emotions, both in the north-south axis (in relation to cognition) as well as in the west-east axis (in relation to social influence), by suggesting a Z axis, in charge of registering emotional depth and involvement.

Este artículo de homenaje a la Profesora Yolanda Ruano se divide en dos partes. En la primera discuto las críticas que ella realizara a mi libro sobre la diosa Fortuna en las que avanzaba su propio análisis de las complejas relaciones entre razón y fortuna en el pensamiento occidental. En la segunda parte, desde el punto de vista del “giro icónico” en humanidades y ciencias sociales, analizo el caso concreto del auge y desaparición de la diosa Fortuna en la iconografía (...) política de la ciudad de Berlín. A lo largo del siglo XIX la diosa Fortuna desaparece de la escena berlinesa y es sustituida por la diosa Niké o Victoria, que popularmente se interpreta como un Ángel de la Victoria. Este es el marco de la infancia de Walter Benjamin, quien más tarde expresará su visión de la historia con un otro ángel completamente distinto, el Angelus Novus de Paul Klee. (shrink)

When a caregiver names objects dominating a child’s view, the association between object and name is unambiguous and children are more likely to learn the object’s name. Children also learn to name things other than solid objects, including nonsolid substances like applesauce. However, it is unknown how caregivers structure linguistic and exploratory experiences with nonsolids to support learning. In this exploratory study of caregivers and children we compare caregiver-child free-play with novel solid objects and novel nonsolid substances to identify the (...) linguistic and exploratory experiences associated with children’s word learning. We found systematic differences in interactions with novel objects, such that children performed more manual actions on solids than nonsolids and caregivers named solids more than nonsolids. Additionally, there was less synchrony between caregivers’ naming and children’s manual and visual exploration of nonsolids than solids. Consistent with prior work, we found that synchronous naming was associated with accurate recognition of solid object names. However, naming synchrony was not associated with recognition of nonsolid substance names or with generalization. Together these findings, though exploratory, suggest the coordination of caregiver-child play can shape what children remember about novel word-object associations for solid objects, but not nonsolid substances. (shrink)

Este artículo se propone describir la dinámica demográfica desde 1997 en Argentina y una provincia por cada región para considerar el impacto de la crisis de 2001-2002 y las etapas posteriores hasta 2016. Los marcos conceptuales elegidos son la transición demográfica y la vulnerabilidad sociodemográfica, a partir de los cuales se identifican perfiles demográficos que representan obstáculos para la mejora de las condiciones de vida (Torrado, 1995; Rodríguez Vignoli, 2001; CEPAL, 2002a y 2002b). A partir de proyecciones de la población (...) y registros de estadísticas vitales (nacimientos y defunciones), se calculan indicadores de mortalidad (esperanza de vida al nacimiento, mortalidad infantil y materna) y fecundidad (tasa global y tasa de fecundidad adolescente), para 1997 y cada año calendario del período 2001-2016. La principal contribución a los estudios de población es el cálculo y análisis de indicadores demográficos anuales, ya que el Instituto Nacional de Estadísticas y Censos sólo publica indicadores de fecundidad y mortalidad provinciales cada diez años, con cada censo de población.Los resultados muestran una evolución positiva de los indicadores demográficos en el país, desde 1997 y luego de la crisis socioeconómica de 2001-2002, aunque con persistencia de las brechas estructurales entre regiones. La esperanza de vida ha crecido en todas las jurisdicciones hasta 2015, cuando comienza a descender en todo el país. La mortalidad infantil disminuye rápidamente en todo el país, particularmente en las provincias más rezagadas. La mortalidad materna se ha reducido claramente en las poblaciones más rezagadas y se muestra inestable en las más avanzadas.La fecundidad general desciende suavemente; la fecundidad adolescente sólo disminuye en las provincias con mayores tasas.El avance en la transición demográfica en Argentina coexiste con situaciones de vulnerabilidad social en todo el país, especialmente en el noreste. Se advierte la sensibilidad de la mortalidad a las crisis económicas experimentadas desde 2008. (shrink)

Synaesthesia is a condition in which one type of stimulation evokes the sensation of another, as when the hearing of a sound produces photisms, i.e. mental percepts of colours. R is a 20 year old colour blind subject who, in addition to the relatively common grapheme-colour synaesthesia, presents a rarely reported cross modal perception in which a variety of visual stimuli elicit aura-like percepts of colour. In R, photisms seem to be closely related to the affective valence of stimuli and (...) typically bring out a consistent pattern of emotional responses. The present case study suggests that colours might be an intrinsic category of the human brain. We developed an empirical methodology that allowed us to study the subject's otherwise inaccessible phenomenological experience. First, we found that R shows a Stroop effect elicited by photisms despite the fact that he does not show a regular Stroop with real colours. Secondly, by manipulating the colour context we confirmed that colours can alter R's emotional evaluation of the stimuli. Furthermore, we demonstrated that R's auras may actually lead to a partially inverted emotional spectrum where certain stimuli bring out emotional reactions opposite to the normal ones. These findings can only be accounted for by considering R's subjective colour experience or qualia. Therefore the present paper defends the view that qualia are a useful scientific concept that can be approached and studied by experimental methods. (shrink)

Food choices are a key determinant of dietary intake, with brain regions, such as the mesolimbic and prefrontal cortex maturing at differential rates into adulthood. More needs to be understood about developmental changes in healthy and unhealthy food perceptions and preference. We investigated how food perceptions and preference vary as a function of age and how food attributes impact age-related changes. One hundred thirty-nine participants completed computerized tasks to rate high-calorie and low-calorie food cues for taste, health, and liking, followed (...) by 100 binary food choices based on each participant’s ratings. Dietary self-control was considered successful when the healthier food was chosen. Self-control success ratio was the proportion of success trials over total number of choices. Beta-weights for health and taste were calculated as each attribute’s influence on food preference. Adiposity measurements included BMI z-score and waist-to-height ratio. High-calorie foods were rated more tasty and less healthy with increasing age. Older participants liked high-calorie foods more, and β-taste was associated with age. Significant age-by-WHtR interactions were observed for health and taste ratings of high-calorie foods, β-taste, and marginally for preference of high-calorie foods. Stratifying by WHtR, we found age-related increases in taste and preference ratings of high-calorie foods in the high WHtR group alone. In contrast, age-related decreases in health ratings of high-calorie foods were significant in the low WHtR group alone. Age and β-taste were significantly associated in the high WHtR group and only marginally significant with low WHtR. Although participants rated low-calorie foods as less tasty and less healthy with increasing age, there was no association between age and preference for low-calorie foods. Participants made faster food choices with increasing age regardless of WHtR, with a significant age-by-WHtR interaction on reaction time. There were no age-related effects in self-control success ratio and β-health. These results suggest that individual differences in age and central adiposity play an important role in preference for high-calorie foods, and a higher importance of food tastiness in food choice may contribute to greater preference for high-calorie foods with increasing age. (shrink)

El propósito de este trabajo, es el de analizar y dar a conocer las obras de arte construidas en mortero de cemento pórtland, que formaron y forman parte del Parque del Pasatiempo de Betanzos (A Coruña). Este Parque fue creado por D. Juan García Naveira con la intención de mostrar, perpetuar y legar a través de los elementos del Pasatiempo, el arte y la cultura de otros países. Un arte que plasmó en estilo ecléctico, inspirado en el arte renacentista, clasicista, (...) barroco y modernista. Entre los materiales más utilizados en su construcción, se encuentra el mortero de cemento pórtland. (shrink)

En una primera aproximación a la obra de Leibniz, podemos tener la impresión de enfrentarnos a una metafísica que sostiene tesis, las cuales, aparte de su enorme dificultad para ser comprendidas, también parecen entrar en conflicto entre sí. Uno de esos casos, particularmente destacado, es el tema de la libertad. En efecto, un sistema que reivindica radicalmente el principio de razón suficiente parece no poder explicar de manera satisfactoria los conceptos de espontaneidad, elección y libertad que quiere atribuir a las (...) acciones humanas. Este ensayo busca aclarar esos conceptos que son fundamentales para una correcta comprensión de la noción leibniziana de libertad. En dicha noción se encuentran fuertemente interconectados tanto elementos provenientes de su metafísica, como sus hallazgos en física y dinámica. A pesar de que estas tesis sobre dinámica son fundamentales para comprender las afirmaciones del autor acerca del tema de la libertad, son precisamente ellas las que suelen pasarse por alto, haciendo que la propuesta de Leibniz aparente cierta inconsistencia. Por el contrario, cuando comprendemos las nociones leibnizianas de fuerza, espontanei dad y elección—y cómo ellas operan en el resto de su sistema metafísico—, entendemos por qué nuestro autor, a pesar de ser un racionalista coherente, ve necesario sostener la libertad humana. Con ello, se pretende mostrar que tal noción es totalmente consistente con el resto de su sistema y cómo ella tiene un buen grado de plausibilidad. (shrink)

We analyze the dynamics of repeated interaction of two players in the Prisoner's Dilemma under various levels of interdependency information and propose an instance-based learning cognitive model to explain how cooperation emerges over time. Six hypotheses are tested regarding how a player accounts for an opponent's outcomes: the selfish hypothesis suggests ignoring information about the opponent and utilizing only the player's own outcomes; the extreme fairness hypothesis weighs the player's own and the opponent's outcomes equally; the moderate fairness hypothesis weighs (...) the opponent's outcomes less than the player's own outcomes to various extents; the linear increasing hypothesis increasingly weighs the opponent's outcomes at a constant rate with repeated interactions; the hyperbolic discounting hypothesis increasingly and nonlinearly weighs the opponent's outcomes over time; and the dynamic expectations hypothesis dynamically adjusts the weight a player gives to the opponent's outcomes, according to the gap between the expected and the actual outcomes in each interaction. When players lack explicit feedback about their opponent's choices and outcomes, results are consistent with the selfish hypothesis; however, when this information is made explicit, the best predictions result from the dynamic expectations hypothesis. (shrink)

The research encompasses the study of ethical and legal issues surrounding the finitude of life. In this sense, topics such as Bioethics were examined to understand the concepts within bioethics, including euthanasia, dystanasia, orthothanasia, mistanasia, and assisted suicide, to build knowledge on the subject. Regarding the methodology, an interdisciplinary and systemic approach was used, involving Ethics, Law, Philosophy, and Health fields, while addressing the following question: What are the main ethical and practical dilemmas involved in preserving the right to a (...) dignified life in the context of extending the life of an incurably ill individual, considering the non-negotiable nature of human dignity? In light of this, the study focused on Bioethics, specifically the conceptual and principled foundation as understood in Bioethics. In this way, aspects related to the finitude of life were addressed in the first instance, using the foundational theory of Ronald Dworkin’s work, presenting the values that correspond to human life in both the legal and personal realms, and attributing the concept of human dignity through a historical analysis leading to its current understanding. (shrink)

Vulnerabilidad educativa en el Gran Córdoba. 2001.

IntroductionTranscranial magnetic stimulation is a consolidated procedure for the treatment of depression, with several meta-analyses demonstrating its efficacy. Theta-burst stimulation is a modification of TMS with similar efficacy and shorter session duration. The geriatric population has many comorbidities and a high prevalence of depression, but few clinical trials are conducted specifically for this age group. TBS could be an option in this population, offering the advantages of few side effects and no pharmacological interactions. Therefore, our aim is to investigate the (...) efficacy of TBS in geriatric depression.Clinical trial registration[https://clinicaltrials.gov/ct2/], identifier [NCT04842929]. (shrink)

There is no doubt that the use of Internet for purchasing products and services has constituted a crucial change in how people go about buying them. In the era of digital transformation, the possibility of accessing information provided by other users about their personal experiences has taken on more weight in the selection and buying processes. On these lines, traditional word-of-mouth has given way to electronic word-of-mouth, which constitutes a major social change. This behavior is particularly relevant in the services (...) area, where potential users cannot in advance assess what is on offer. There is an abundant literature analyzing the effects of eWOM on different variables of interest in this sector. However, little is known about the factors that determine eWOM. Thus, the main objective of the present paper is to analyze the impact of two variables on eWOM. Both of them are crucial for potential customers in the process of finding hotel accommodations and they can motivate people to make such comments. The results demonstrate that these variables truly have a significant impact on whether or not users make comments on line. Moreover, it proved possible to observe certain differences according to the profile of the tourist involved and the destination where the hotel is located. In the current changing environment, this information is of great use for hotel managers in order to design strategies according to the type of guest they wish to attract. (shrink)

RésuméDepuis les débuts de l'humanité, l'être humain s'est préoccupé de conserver les aliments en vue de les rendre plus longtemps comestibles. Au fil du temps, différentes méthodes pour préserver la nourriture ont été découvertes et perfectionnées, et ces techniques se trouvent décrites dans beaucoup d'œuvres. Ce travail décrit la connaissance des techniques de conservation qu'avaient les habitants de la péninsule ibérique ainsi que les développements qu'ils leur ont apportés. Il s'attache à étudier les divers procédés mis au point entre leieret (...) lexviesiècle, de façon à évaluer leur apport historique respectif. Les œuvres choisies et consultées sont : L.J.M. Columela,Los doce libros de Agricultura, Abū al-Jayr,Kitāb al-Filāḥa. Tratado de agricultura, Ibn Baṣṣāl,Kitāb al-Filāḥa. Libro de agricultura, Ibn al-ʿAwwām,Kitāb al-Filāḥa. Libro de Agricultura, Ibn Luyūn,Kitāb al-Filāḥa. Tratado de Agricultura, Alonso de Herrera,Agricultura general. (shrink)

La sostenibilidad es un modelo de desarrollo en el que las acciones presentes no deben comprometer el futuro de las generaciones venideras, y se vincula con un desarrollo económico y social respetuoso con el medio ambiente. El enoturismo supone un modo de ocio placentero que conjuga el placer del disfrute de los vinos con aspectos relacionados con la cultura, como conocimientos sobre elaboración de los vinos, sobre los ecosistemas asociados a los viñedos, sobre expresiones artísticas, etc. Todo ello constituye parte (...) del desarrollo cultural de las regiones vitivinícolas, en las que la cultura del vino ha marcado su devenir histórico y lo que son hoy en día. Por tanto, se puede afirmar que la cultura del vino, y su uso a través de las experiencias enoturísticas, está claramente relacionada con la sostenibilidad social, económica, ambiental y cultural de los territorios. (shrink)

In his famous letter to A. N. Prior dated 3 September 1958, Saul Kripke suggested the use of branching time in temporal logic. In this paper, however, it is argued that Prior worked with an idea close to the notion of branching time (‘the big Y’) already the year before he received Kripke’s letter. It is likely that Prior’s findings based on this early study can explain why Prior so quickly accepted the idea of branching time when he received Kripke’s (...) letter. (shrink)

One of the main challenges in medicine is to guarantee an appropriate drug supply according to the real needs of patients. Closed-loop strategies have been widely used to develop automatic solutions based on feedback variables. However, when the variable of interest cannot be directly measured or there is a lack of knowledge behind the process, it turns into a difficult issue to solve. In this research, a novel algorithm to approach this problem is presented. The main objective of this study (...) is to provide a new general algorithm capable of determining the influence of a certain clinical variable in the decision making process for drug supply and then defining an automatic system able to guide the process considering this information. Thus, this new technique will provide a way to validate a given physiological signal as a feedback variable for drug titration. In addition, the result of the algorithm in terms of fuzzy rules and membership functions will define a fuzzy-based decision system for the drug delivery process. The method proposed is based on a Fuzzy Inference System whose structure is obtained through a decision tree algorithm. A four-step methodology is then developed: data collection, preprocessing, Fuzzy Inference System generation, and the validation of results. To test this methodology, the analgesia control scenario was analysed. Specifically, the viability of the Analgesia Nociception Index as a guiding variable for the analgesic process during surgical interventions was studied. Real data was obtained from fifteen patients undergoing cholecystectomy surgery. (shrink)